| 英文名稱 | Rabbit MET Polyclonal Antibody |
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| 應(yīng)用2 | WB |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | AUTS9;DFNB97;HGFR;RCCP2;c-Met
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| 應(yīng)用 | WB |
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| 稀釋比例 | WB1:500-1:2000 |
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| 交叉反應(yīng) | Human |
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| 蛋白分子量 | 156kDa |
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| Gene ID | 4233 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human MET |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P08581 |
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| 克隆類型 | Polyclonal Antibody |
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| 來(lái)源 | Rabbit |
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| 背景資料 | This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. |
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