英文名稱 | Rabbit SLC9A3R1 Polyclonal Antibody |
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應(yīng)用2 | WB |
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克隆類型2 | Monoclonal Antibody |
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別名 | EBP50;NHERF;NHERF-1;NHERF1;NPHLOP2
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應(yīng)用 | WB |
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稀釋比例 | WB1:1000-1:4000 |
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交叉反應(yīng) | Human Mouse Rat |
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蛋白分子量 | 39kDa |
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Gene ID | 9368 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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亞型 | IgG |
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免疫原 | Recombinant protein of human SLC9A3R1 |
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性狀 | Lyophilized or Liquid |
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Swiss Prot | O14745 |
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來源 | Rabbit |
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背景資料 | This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. |
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