| 英文名稱 | Rabbit TRAF1 Polyclonal Antibody |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | EBI6;MGC:10353
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| 應(yīng)用 | WB |
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| 稀釋比例 | WB1:500-1:2000 |
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| 交叉反應(yīng) | Human Mouse Rat |
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| 蛋白分子量 | 46kDa |
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| Gene ID | 7185 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human TRAF1 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | Q13077 |
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| 克隆類型 | Polyclonal Antibody |
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| 來(lái)源 | Rabbit |
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| 背景資料 | The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. |
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