英文名稱 | Rabbit HDAC4 Polyclonal Antibody |
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應(yīng)用2 | WB IHC IF IP ChIP |
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克隆類型2 | Polyclonal Antibody |
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別名 | AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA
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應(yīng)用 | WB,IHC,IF,IP,ChIP |
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稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 IP1:50-1:200Ch IP1:20-1:100 |
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交叉反應(yīng) | Human Mouse Rat |
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蛋白分子量 | 119kDa |
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Gene ID | 9759 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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純化方法 | Affinity purification |
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亞型 | IgG |
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免疫原 | A synthetic peptide of human HDAC4 |
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性狀 | Lyophilized or Liquid |
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Swiss Prot | P56524 |
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克隆類型 | Polyclonal Antibody |
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來源 | Rabbit |
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背景資料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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