| 英文名稱 | Rabbit CDKN1B Polyclonal Antibody |
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| 應用2 | WB IHC IF |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | CDKN4;KIP1;MEN1B;MEN4;P27KIP1
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| 應用 | WB,IHC,IF |
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| 稀釋比例 | WB1:200-1:500 IHC1:50-1:200 IF1:20-1:50 |
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| 交叉反應 | Human Mouse Rat |
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| 蛋白分子量 | 22kDa |
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| Gene ID | 1027 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human CDKN1B |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P46527 |
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| 克隆類型 | Polyclonal Antibody |
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| 來源 | Rabbit |
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| 背景資料 | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
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