| 英文名稱 | Rabbit TCF3 Polyclonal Antibody |
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| 應用2 | WB IHC FC |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | AGM8;E2A;E47;ITF1;TCF-3;VDIR;bHLHb21
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| 應用 | WB,IHC,FC |
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| 稀釋比例 | WB1:500-1:2000 IHC1:50-1:100FC 1:20-1:50 |
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| 交叉反應 | Human Mouse |
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| 蛋白分子量 | 68kDa |
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| Gene ID | 6929 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human TCF3 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P15923 |
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| 克隆類型 | Polyclonal Antibody |
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| 來源 | Rabbit |
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| 背景資料 | This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. |
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