| 英文名稱 | Rabbit PKN1 Polyclonal Antibody |
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| 應用2 | WB IHC |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | DBK;PAK-1;PAK1;PKN;PKN-ALPHA;PRK1;PRKCL1
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| 應用 | WB,IHC |
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| 稀釋比例 | WB1:500-1:1000 IHC1:50-1:100 |
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| 交叉反應 | Human Mouse Rat |
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| 蛋白分子量 | 104kDa |
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| Gene ID | 5585 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human PKN1 |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | Q16512 |
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| 克隆類型 | Polyclonal Antibody |
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| 來源 | Rabbit |
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| 背景資料 | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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