英文名稱 | Rabbit P4HB Polyclonal Antibody |
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應(yīng)用2 | WB IHC IF IP RIP |
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克隆類型2 | Polyclonal Antibody |
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別名 | CLCRP1;DSI;ERBA2L;GIT;P4Hbeta;PDI;PDIA1;PHDB;PO4DB;PO4HB;PROHB
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應(yīng)用 | WB,IHC,IF,IP,RIP |
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稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:20-1:100 IP1:50-1:100R IP1:20-1:50 |
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交叉反應(yīng) | Human Mouse Rat |
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蛋白分子量 | 57kDa |
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Gene ID | 5034 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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純化方法 | Affinity purification |
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亞型 | IgG |
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免疫原 | Recombinant protein of human P4HB |
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性狀 | Lyophilized or Liquid |
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Swiss Prot | P07237 |
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克隆類型 | Polyclonal Antibody |
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來源 | Rabbit |
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背景資料 | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. |
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