英文名稱 | Rabbit SOCS3 Polyclonal Antibody |
---|
別名 | ATOD4;CIS3;Cish3;SOCS-3;SSI-3;SSI3
|
---|
應(yīng)用 | WB |
---|
稀釋比例 | WB1:500-1:2000 |
---|
交叉反應(yīng) | Human Mouse Rat |
---|
蛋白分子量 | 25kDa |
---|
Gene ID | 9021 |
---|
保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
---|
儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
---|
純化方法 | Affinity purification |
---|
亞型 | IgG |
---|
免疫原 | A synthetic peptide of human SOCS3 |
---|
性狀 | Lyophilized or Liquid |
---|
Swiss Prot | O14543 |
---|
克隆類型 | Polyclonal Antibody |
---|
來源 | Rabbit |
---|
背景資料 | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. |
---|