英文名稱 | Rabbit MMP7 Polyclonal Antibody |
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應(yīng)用2 | WB IHC |
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克隆類型2 | Monoclonal Antibody |
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別名 | MMP-7;MPSL1;PUMP-1
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應(yīng)用 | WB,IHC |
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稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 |
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交叉反應(yīng) | Human Mouse Rat |
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蛋白分子量 | 30kDa |
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Gene ID | 4316 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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純化方法 | Affinity purification |
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亞型 | IgG |
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免疫原 | Recombinant protein of human MMP7 |
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性狀 | Lyophilized or Liquid |
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Swiss Prot | P09237 |
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克隆類型 | Polyclonal Antibody |
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來(lái)源 | Rabbit |
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背景資料 | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.
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