英文名稱 |
Rabbit ITGA4 Polyclonal Antibody |
---|
應(yīng)用2 |
WB IHC |
克隆類型2 |
Polyclonal Antibody |
別名 |
CD49D;IA4
|
應(yīng)用 |
WB,IHC |
稀釋比例 |
WB1:500-1:2000 IHC1:50-1:200 |
交叉反應(yīng) |
Human Mouse Rat |
蛋白分子量 |
115kDa |
Gene ID |
3676 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
儲存液 |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
純化方法 |
Affinity purification |
亞型 |
IgG |
免疫原 |
A synthetic peptide of human ITGA4 |
性狀 |
Lyophilized or Liquid |
Swiss Prot |
P13612 |
克隆類型 |
Polyclonal Antibody |
來源 |
Rabbit |
背景資料 |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |