英文名稱 | Rabbit ITGA4 Polyclonal Antibody |
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應(yīng)用2 | WB IHC |
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克隆類型2 | Polyclonal Antibody |
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別名 | CD49D;IA4
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應(yīng)用 | WB,IHC |
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稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 |
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交叉反應(yīng) | Human Mouse Rat |
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蛋白分子量 | 115kDa |
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Gene ID | 3676 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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純化方法 | Affinity purification |
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亞型 | IgG |
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免疫原 | A synthetic peptide of human ITGA4 |
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性狀 | Lyophilized or Liquid |
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Swiss Prot | P13612 |
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克隆類型 | Polyclonal Antibody |
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來源 | Rabbit |
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背景資料 | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
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