Anti-P27 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-06-21
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號(hào) |
K106720P
|
| 應(yīng)用范圍 |
IHC
|
| CAS編號(hào) |
|
| 抗體名 |
Anti-P27 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點(diǎn) |
|
| 適應(yīng)物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標(biāo)識(shí)物 |
CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1
|
| 濃度 |
%
|
| 免疫原 |
Recombinant protein of human P27
|
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)
