Anti-IRAK4 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-06-21
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K106734P
|
應(yīng)用范圍 |
WB IHC
|
CAS編號 |
|
抗體名 |
Anti-IRAK4 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
IRAK-4;Renal carcinoma antigen NY-REN-64;Interleukin-1 receptor-associated kinase 4
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human IRAK4
|
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.