Anti-AKR1C3 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-06-21
產(chǎn)品詳請(qǐng)
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號(hào) |
K106744P
|
應(yīng)用范圍 |
WB
|
CAS編號(hào) |
|
抗體名 |
Anti-AKR1C3 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識(shí)物 |
DDX;HAKRB;HSD17B5;KIAA0119;PGFS
|
濃度 |
%
|
免疫原 |
Recombinant protein of human AKR1C3
|
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.