Anti-TRP12 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-06-21
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106822P
|
| 應(yīng)用范圍 |
WB IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-TRP12 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點(diǎn) |
|
| 適應(yīng)物種 |
Human Mouse Rat
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標(biāo)識物 |
VRL2;?VROAC;TRPV4
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human TRP12
|
This protein play a important role in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by heat, low pH, citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers.
