Anti-NSMCE2 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-06-21
產(chǎn)品詳請(qǐng)
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號(hào) |
K106963P
|
應(yīng)用范圍 |
WB
|
CAS編號(hào) |
|
抗體名 |
Anti-NSMCE2 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識(shí)物 |
C8orf36;E3 SUMO protein ligase NSE2;hMMS21;MMS21;MMS21 homolog;Non SMC element 2 homolog;NSE2;NSMCE2
|
濃度 |
%
|
免疫原 |
Recombinant protein of human NSMCE2
|
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.?