Anti-TRF1 Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-06-21
產(chǎn)品詳請(qǐng)
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號(hào) |
K107057P
|
應(yīng)用范圍 |
IHC
|
CAS編號(hào) |
|
抗體名 |
Anti-TRF1 Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
|
適應(yīng)物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識(shí)物 |
Telomeric repeat-binding factor;1PIN2;TRBF1;TRF;TRF1
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human TRF1
|
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.