Anti-PSMC6 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-06-20
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K107080P
|
| 應用范圍 |
WB IHC
|
| CAS編號 |
|
| 抗體名 |
Anti-PSMC6 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
|
| 適應物種 |
Human Mouse Rat
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
CADP44;p42;P44;Proteasome subunit p42;PSMC6;Rpt4;SUG2
|
| 濃度 |
%
|
| 免疫原 |
Recombinant protein of human PSMC6
|
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
