Anti-CENPH Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-06-20
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K107107P
|
應用范圍 |
WB IHC
|
CAS編號 |
|
抗體名 |
Anti-CENPH Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應物種 |
Human
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標識物 |
CENP H;CENPH;centromere protein H;ICEN35;NNF1;PMF1
|
濃度 |
%
|
免疫原 |
Recombinant protein of human CENPH
|
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.